3.35B: Understand How a Change in DNA can Affect the Phenotype by Altering the Sequence of Amino Acids in Protein

EFFECT OF CHANGE IN DNA ON PHENOTYPE:

AMINO ACIDS AND PROTEIN

Diagram Showing How a Protein is Produced

EXPLANATION: Mutations involving the change in DNA sequence can affect the structure and function of Proteins For Protein synthesis to occur, DNA sequence needs to be transcribed and translated Hence, when mutations change the base sequence of DNA, this will change the base sequence of the complementary mRNA transcript As a result, modified mRNA transcript will be translated to code for different Amino acids, changing the structure of the Polypeptide chain Consequently, the function of Protein is altered